Eve first appeared on the Bulworth soundtrack as EVE of destruction while signed to Dr Dre's Aftermath Entertainment she did not see much action with big releases soon coming from Dr Dre so she grouped up with DMX and the Ruff Ryders on her first single as a ruff ryder DJ Clue's The Professional, along with other Ruff Ryders' compilations.
Her next single, "What Ya Want", featuring Nokio the N-Tity of Dru Hill, became a top 40 hit on the U.S. Billboard 200 peaking at 29. Her 1999 debut, Let There Be Eve...Ruff Ryders' First Lady, was an unprecedented success, becoming the first rap album by a woman to enter the Billboard 200 at number one.
The follow-up to Ruff Ryders' First Lady, Scorpion, was released in 2001. Its first single, "Who's That Girl" guaranteed the rapper first international success. The second single, "Let Me Blow Ya Mind" (with Gwen Stefani of No Doubt and produced by Dr. Dre co-written by then-boyfriend Stevie J.), became a pop success, peaking at number two on the Billboard Hot 100. The song won a Grammy Award for Best Rap/Sung Collaboration, and Eve eventually went platinum.
Eve's third album, Eve-Olution, was released in summer 2002 (see 2002 in music) and peaked at number six on the Billboard 200. In the meantime, the album's first single, "Gangsta Lovin'", with Alicia Keys, became another number two hit. The second and final single, "Satisfaction", only saw moderate success again.
In 2005, the rapper appeared on Gwen Stefani's cover version of Louchie Lou & Michie One song "Rich Girl", which peaked at number seven on the Billboard Hot 100 in March. The same year, she appeared on the remix of Amerie's number one U.S. R&B hit, "1 Thing" the Hitch soundtrack. Eve also was featured in Keyshia Cole's song "Never" as on the Barbershop 2: Back in Business soundtrack and The Way It Is along with the official remix for Teairra Mari's second single, "No Daddy".
In 2007, she appeared on Kelly Rowland's single "Like This". The Punk Cabaret band One On None covered Eve's 1999 song "Love Is Blind". In July 2007, Eve made a guest appearance on Maroon 5's second single Wake Up Call on Live @ 45th at Night, it is unknown if this will be an official remix or if it will even be recorded. In late 2008, she sung the song "Set It On Fire", which was featured on the credits for the movieTransporter 3 and is available on the Transporter 3 soundtrack.
In late 2010 Eve was the featured rapper on Australian singer Guy Sebastian's single "Who's That Girl", which has reached number one on the ARIA Singles Chart, and achieved platinum certification. It is Eve's first number one single in Australia. Eve began work on a new album title Here I Am. In May 2007, XXL magazine profiled six recorded tracks from Here I Am. Five of them were produced by Swizz Beatz, including singles "Tambourine" and "Give It To You" (featuring Sean Paul). Pharrell Williams produced "All Night Long". In contrast to most of the tracks, Eve sings rather than raps on "All Night Long". XXL published a review of the original Here I Am in July, rating it an L in its "shoe size" rating system ranging from S to XXL. However the album ran into a series of delays due to corporate change at the record label and discontent with the lackluster success of the first and second singles, "Tambourine", released in April 2007, and "Give It to You" (featuring Sean Paul), released later. She recently appeared on Ludacris' new album Battle Of The Sexes in the remix of "My Chick Bad" with fellow female rappers Trina and Diamond. Recently on the Hennessy Artistry Tour, Eve stated that the album will be released March 2011 via EMI. In April 2011, Eve featured in Timati's new song and video "Money in the Bank". As Eve has featured in many singles in 2011, it has raised speculation that she is releasing Lip Lock in 2011.